Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | CNR1 | P21554 | 4/20 | 0.39 |
| ▸ | CNR2 | P34972 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9559516 | 0.86 | TSHR (0.38) | TSHRMAPK1MEN1KMT2ACNR1 | |
| SCHEMBL8746210 | 0.82 | CNR2 (0.47) | CNR1CNR2ALDH1A1 | |
| SCHEMBL26921504 | 0.81 | TSHR (0.41) | TSHRMAPK1MEN1KMT2ACNR1 | |
| SCHEMBL4666901 | 0.79 | — | — | |
| SCHEMBL5223296 | 0.77 | MEN1 (0.42) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL10354087 | 0.77 | MEN1 (0.42) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL8618313 | 0.76 | CNR2 (0.50) | CNR1CNR2ALDH1A1 | |
| SCHEMBL8618271 | 0.76 | CNR2 (0.50) | CNR1CNR2ALDH1A1 | |
| SCHEMBL12369626 | 0.76 | CNR2 (0.50) | CNR1CNR2ALDH1A1 | |
| SCHEMBL19543504 | 0.76 | MEN1 (0.42) | TSHRMAPK1MEN1KMT2ACNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |