Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MME | P08473 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ACE | P12821 | 1/20 | 0.34 |
| ▸ | CPA1 | P15085 | 1/20 | 0.34 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.34 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.30 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29143263 | 1.00 | TP53 (0.40) | TP53ALDH1A1MMERAB9AACE | |
| SCHEMBL28345778 | 1.00 | TP53 (0.40) | TP53ALDH1A1MMERAB9AACE | |
| SCHEMBL28335091 | 1.00 | TP53 (0.40) | TP53ALDH1A1MMERAB9AACE | |
| SCHEMBL3978172 | 0.97 | TP53 (0.42) | TP53ALDH1A1MMERAB9AACE | |
| SCHEMBL3978169 | 0.97 | TP53 (0.42) | TP53ALDH1A1MMERAB9AACE | |
| SCHEMBL23611031 | 0.94 | TP53 (0.40) | TP53ALDH1A1MMERAB9AACE | |
| SCHEMBL29478439 | 0.94 | TP53 (0.40) | TP53ALDH1A1MMERAB9AACE | |
| Lactic Acid SCHEMBL31468110 | 0.87 | TP53 (0.55) | TP53ALDH1A1MMERAB9AACE | |
| SCHEMBL4572684 | 0.84 | TP53 (0.47) | TP53MMERAB9AACECPA1 | |
| SCHEMBL2807366 | 0.84 | TP53 (0.47) | TP53MMERAB9AACECPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108473484-B | Compounds useful as TRPM8 modulators | 弗门尼舍公司 | 2021-06-29 | — | — | CN | disclosed |