SCHEMBL28588993

SCHEMBL28588993

COC(O)(OC)c1ccc(Cl)cc1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.56
KMT2A Q03164 4/20 0.56
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
HIF1A Q16665 1/20 0.50
CYP19A1 P11511 4/20 0.43
NPSR1 Q6W5P4 4/20 0.42
HTT P42858 2/20 0.42
LMNA P02545 3/20 0.40
BCL2 P10415 1/20 0.40
GRIN2D O15399 1/20 0.40
GRIN3B O60391 1/20 0.40
GRIN1 Q05586 1/20 0.40
GRIN2A Q12879 1/20 0.40
GRIN2B Q13224 1/20 0.40
GRIN2C Q14957 1/20 0.40
GRIN3A Q8TCU5 1/20 0.40
POLB P06746 2/20 0.38
CYP2A6 P11509 1/20 0.38
CYP1A2 P05177 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28555994 0.77 CYP2C9 (0.52) MEN1KMT2AMAPK1HIF1ANPSR1
SCHEMBL319709 0.75 CES1 (0.47) KMT2ATSHRMAPK1CYP1A2CYP3A4
SCHEMBL8824095 0.75 MEN1 (0.48) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL1817529 0.75 MEN1 (0.48) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL2860836 0.73 TSHR (0.74) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL17532646 0.73 MEN1 (0.52) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL10840347 0.73 MEN1 (0.52) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL4297794 0.72 MEN1 (0.71) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL26402 0.72 MEN1 (1.00) MEN1KMT2ATSHRMAPK1HIF1A
SCHEMBL1016971 0.72 KMT2A (0.71) MEN1KMT2ATSHRMAPK1HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113087672-A Preparation method of ambroxol impurity 广州隽沐生物科技股份有限公司 2021-07-09 CN disclosed