Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 3/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | SRC | P12931 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28571047 | 0.89 | SLC22A12 (0.79) | SLC22A12KDM4EHSD17B10CNR2NR4A2 | |
| SCHEMBL28577788 | 0.89 | SLC22A12 (0.79) | SLC22A12KDM4EHTTCNR2LMNA | |
| SCHEMBL29929026 | 0.89 | SLC22A12 (0.79) | SLC22A12KDM4EHTTCNR2LMNA | |
| SCHEMBL28589203 | 0.86 | SLC22A12 (0.65) | SLC22A12KDM4EHSD17B10CNR2NR4A2 | |
| SCHEMBL28584060 | 0.85 | KDM4E (0.62) | SLC22A12KDM4EHSD17B10HTTCNR2 | |
| SCHEMBL28595217 | 0.85 | SLC22A12 (0.63) | SLC22A12KDM4EHSD17B10CNR2NR4A2 | |
| SCHEMBL28584067 | 0.84 | CNR2 (0.59) | SLC22A12KDM4EHSD17B10CNR2NR4A2 | |
| SCHEMBL28595214 | 0.84 | SLC22A12 (0.60) | SLC22A12KDM4EHSD17B10CNR2NR4A2 | |
| SCHEMBL28589205 | 0.83 | SLC22A12 (0.62) | SLC22A12KDM4EHSD17B10CNR2NR4A2 | |
| SCHEMBL28584112 | 0.81 | SLC22A12 (0.58) | SLC22A12KDM4EHTTCNR2NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113004188-B | Indole derivative, preparation method and application | 沈阳药科大学 | 2022-09-20 | — | — | CN | disclosed |
| CN-113004188-A | Indole derivative, preparation method and application | 沈阳药科大学 | 2021-06-22 | — | — | CN | disclosed |