Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28338970 | 1.00 | ATM (0.39) | ATMF2PRSS1PRSS2PRSS3 | |
| SCHEMBL20241327 | 1.00 | ATM (0.39) | ATMF2PRSS1PRSS2PRSS3 | |
| SCHEMBL28603834 | 1.00 | ATM (0.39) | ATMF2PRSS1PRSS2PRSS3 | |
| SCHEMBL28681081 | 1.00 | ATM (0.39) | ATMF2PRSS1PRSS2PRSS3 | |
| SCHEMBL22229916 | 1.00 | ATM (0.39) | ATMF2PRSS1PRSS2PRSS3 | |
| SCHEMBL25361139 | 0.87 | ATM (0.37) | ATM | |
| SCHEMBL3402484 | 0.87 | ATM (0.37) | ATM | |
| SCHEMBL28596580 | 0.87 | ATM (0.37) | ATM | |
| SCHEMBL28598994 | 0.87 | ATM (0.37) | ATM | |
| SCHEMBL28341482 | 0.87 | ATM (0.37) | ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121562-B | Polycyclic compounds as inhibitors of bruton's tyrosine kinase | 詹森药业有限公司 | 2022-09-13 | — | — | CN | disclosed |
| CN-113924292-A | Antimicrobial compounds and methods | 库扎环球有限责任公司 | 2022-01-11 | — | — | CN | disclosed |
| CN-113121562-A | Polycyclic compounds as inhibitors of bruton's tyrosine kinase | 詹森药业有限公司 | 2021-07-16 | — | — | CN | disclosed |