SCHEMBL28592603

SCHEMBL28592603

N#Cc1ccc(-c2ccccc2)cc1-c1nc(C2CCCN2C#N)no1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ USP30 Q70CQ3 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28592601 1.00 USP30 (0.76) USP30
SCHEMBL19400851 0.86 USP30 (1.00) USP30
SCHEMBL29562278 0.86 USP30 (1.00) USP30
SCHEMBL19400798 0.86 USP30 (1.00) USP30
SCHEMBL29562223 0.85 USP30 (1.00) USP30
SCHEMBL22555672 0.85 USP30 (1.00) USP30
SCHEMBL29562315 0.82 USP30 (0.84) USP30
SCHEMBL22555620 0.82 USP30 (0.84) USP30
SCHEMBL22555621 0.82 USP30 (0.84) USP30
SCHEMBL19385347 0.79 USP30 (1.00) USP30

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108884068-B 1-cyano-pyrrolidine derivatives as DUB inhibitors 特殊治疗有限公司 2021-02-26 — — CN claimed
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