SCHEMBL2859306

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2871497	0.91	NR1H2 (0.51)	MAP2K4NR1H2SRCRIPK2NR1H3
	SCHEMBL2862700	0.84	SRC (0.39)	SRCRIPK2
	SCHEMBL2858091	0.84	MAP2K4 (0.56)	MAP2K4NR1H2NR1H3
	SCHEMBL1513042	0.82	MAP2K4 (0.48)	MAP2K4NR1H2NR1H3
	SCHEMBL22801607	0.81	MAP2K4 (0.48)	MAP2K4NR1H2NR1H3
	SCHEMBL22801564	0.80	MAP2K4 (0.55)	MAP2K4NR1H2RIPK2
	SCHEMBL9951686	0.77	MAP2K4 (0.40)	MAP2K4NR1H2NR1H3
	SCHEMBL13375156	0.75	MAP2K4 (0.39)	MAP2K4NR1H2NR1H3
	SCHEMBL2862273	0.75	MAP2K4 (0.55)	MAP2K4NR1H2
	SCHEMBL13198131	0.75	MAP2K4 (0.55)	MAP2K4NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.