SCHEMBL28593181

SCHEMBL28593181

CCCC[Si](O)(CCCC)CCCC.[Zr]

nearest known ligand 0.38

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.38
LMNA P02545 3/20 0.38
ALDH1A1 P00352 2/20 0.37
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
HSD17B10 Q99714 1/20 0.33
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
CES2 O00748 2/20 0.32
CES1 P23141 2/20 0.32
ANPEP P15144 1/20 0.32
EPHX1 P07099 2/20 0.31
AR P10275 1/20 0.30
TDP1 Q9NUW8 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL272672 0.97 TSHR (0.40) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL8778115 0.93 TSHR (0.38) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL28586451 0.93 TSHR (0.38) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL3482286 0.90 TSHR (0.35) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL3482195 0.90 TSHR (0.35) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL618894 0.87 TSHR (0.44) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL17090784 0.84 TSHR (0.50) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL3481973 0.84 TSHR (0.35) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL10984369 0.84 TSHR (0.50) TSHRLMNAALDH1A1THRBSMN1; SMN2
SCHEMBL2922266 0.84 TSHR (0.50) TSHRLMNAALDH1A1THRBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108291031-B Polymetaloxane, method for producing same, composition thereof, cured film, method for producing same, member provided with same, and electronic component 东丽株式会社 2021-06-15 CN disclosed