SCHEMBL28593227

SCHEMBL28593227

COC(=O)CCCCC(C)(C)C#N

nearest known ligand 0.50

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.50
LMNA P02545 4/20 0.46
ALDH1A1 P00352 1/20 0.46
RECQL P46063 1/20 0.41
CNR1 P21554 1/20 0.38
CNR2 P34972 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.37
KMT2A Q03164 3/20 0.36
MEN1 O00255 2/20 0.34
CA12 O43570 1/20 0.33
CA14 Q9ULX7 1/20 0.33
GLA P06280 1/20 0.33
KDM4E B2RXH2 1/20 0.33
EPHX2 P34913 1/20 0.33
PKM P14618 1/20 0.33
HPGD P15428 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18155288 0.94 TSHR (0.52) TSHRLMNAALDH1A1RECQLCNR1
SCHEMBL15159952 0.86 TSHR (0.48) TSHRLMNAALDH1A1RECQLCNR1
SCHEMBL28642072 0.82 CYP1A2 (0.47) TSHRALDH1A1KMT2AMEN1
SCHEMBL20691171 0.78 POLB (0.44) TSHRLMNAALDH1A1CA12CA14
SCHEMBL1909002 0.78 TSHR (0.61) TSHRLMNAALDH1A1RECQLCNR1
Ethylene SCHEMBL29250348 0.77 TSHR (0.54) TSHRLMNAALDH1A1RECQLCNR1
SCHEMBL5503646 0.76 CYP1A2 (0.48) TSHRALDH1A1L3MBTL1KMT2AMEN1
SCHEMBL24383921 0.76 TSHR (0.58) TSHRLMNAALDH1A1RECQLCNR1
SCHEMBL10611084 0.76 TSHR (0.58) TSHRLMNAALDH1A1RECQLCNR1
SCHEMBL2254876 0.76 TSHR (0.58) TSHRLMNAALDH1A1RECQLCNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116143658-A Method for simultaneously preparing tripropylacetonitrile, tripropylamide and tripropylacetic acid 上海青平药业有限公司 2023-05-23 CN claimed
CN-116143658-A Method for simultaneously preparing tripropylacetonitrile, tripropylamide and tripropylacetic acid 上海青平药业有限公司 2023-05-23 CN disclosed
CN-113200848-A Novel preparation method of valproic acid 上海青平药业有限公司 2021-08-03 CN disclosed
CN-113200844-A Preparation method of sodium valproate 上海青平药业有限公司 2021-08-03 CN disclosed
CN-113173845-A Method for preparing valproic acid 上海青平药业有限公司 2021-07-27 CN disclosed
CN-113149823-A 2-R1Preparation method of valeric acid 上海青平药业有限公司 2021-07-23 CN disclosed