Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 3/20 | 0.54 |
| ▸ | MASP2 | O00187 | 2/20 | 0.48 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 6/20 | 0.41 |
| ▸ | BUB1 | O43683 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30387402 | 1.00 | F2 (0.54) | F2MASP2AAK1NAMPTBUB1 | |
| SCHEMBL23478384 | 1.00 | F2 (0.54) | F2MASP2AAK1NAMPTBUB1 | |
| Trifluoroacetic Acid SCHEMBL30632844 | 0.95 | F2 (0.53) | F2MASP2AAK1NAMPTBUB1 | |
| SCHEMBL23478663 | 0.87 | SMN1; SMN2 (0.48) | F2NAMPTCYP2C9SMN1; SMN2CYP3A4 | |
| SCHEMBL30632885 | 0.87 | SMN1; SMN2 (0.48) | F2NAMPTCYP2C9SMN1; SMN2CYP3A4 | |
| SCHEMBL23452548 | 0.85 | F2 (0.61) | F2MASP2NAMPTCYP2C9SMN1; SMN2 | |
| SCHEMBL23452545 | 0.85 | F2 (0.61) | F2MASP2NAMPTCYP2C9SMN1; SMN2 | |
| Trifluoroacetic Acid SCHEMBL23452474 | 0.82 | F2 (0.57) | F2MASP2NAMPTCYP2C9CYP3A4 | |
| SCHEMBL23461311 | 0.79 | F2 (0.52) | F2MASP2NAMPTCYP2C9SMN1; SMN2 | |
| SCHEMBL23461309 | 0.79 | F2 (0.52) | F2MASP2NAMPTCYP2C9SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112867706-A | MASP-2 inhibitors and methods of use | 奥默罗斯公司 | 2021-05-28 | — | — | CN | disclosed |