SCHEMBL28594841

SCHEMBL28594841

C[C@@H](c1ccccn1)[C@H](CO[Si](C)(C)C(C)(C)C)N[S@+]([O-])C(C)(C)C

nearest known ligand 0.31

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CASR P41180 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28594847 1.00 CASR (0.31) CASRTSHR
SCHEMBL28594844 1.00 CASR (0.31) CASRTSHR
SCHEMBL28583876 0.87 KCNA5 (0.30)
SCHEMBL28583875 0.87 KCNA5 (0.30)
SCHEMBL20284950 0.87 KCNA5 (0.30)
SCHEMBL1439441 0.85 TSHR (0.32) CASRTSHR
SCHEMBL10276865 0.85 TSHR (0.32) CASRTSHR
SCHEMBL20333071 0.78
SCHEMBL20285112 0.78
SCHEMBL20279049 0.78 KCNA5 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107709301-B Pyrazole derivative or pharmacologically acceptable salt thereof 橘生药品工业株式会社 2021-06-22 CN disclosed