Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 19/20 | 0.43 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | PLG | P00747 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.38 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GMNN | O75496 | 1/20 | 0.38 |
| ▸ | EGFR | P00533 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | TACR2 | P21452 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2855297 | 0.94 | PPARG (0.45) | PPARGPPARAMEN1GMNNEGFR | |
| SCHEMBL2858447 | 0.92 | PPARG (0.43) | PPARGPPARAPLGPRSS1PRSS2 | |
| SCHEMBL2847839 | 0.91 | PPARG (0.47) | PPARGPPARAMEN1GMNNEGFR | |
| SCHEMBL2854100 | 0.90 | PPARG (0.46) | PPARGPPARAMEN1GMNNEGFR | |
| SCHEMBL2849454 | 0.90 | PPARG (0.48) | PPARGPPARAMEN1GMNNEGFR | |
| SCHEMBL2849756 | 0.88 | PPARG (0.48) | PPARG | |
| SCHEMBL2852146 | 0.88 | PPARG (0.51) | PPARGPPARAMEN1GMNNEGFR | |
| SCHEMBL2852151 | 0.88 | PPARG (0.51) | PPARGPPARAMEN1GMNNEGFR | |
| SCHEMBL2854583 | 0.87 | PPARG (0.45) | PPARGPLGPRSS1PRSS2PRSS3 | |
| SCHEMBL2854577 | 0.87 | PPARG (0.45) | PPARGPLGPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1575911-B1 | BIAROMATIC COMPOUNDS WHICH ACTIVATE PPAR-GAMMA TYPE RECEPTORS AND USE THEREOF IN COSMETIC OR PHARMACEUTICAL COMPOSITIONS | GALDERMA RES & DEV (FR) | 2010-01-13 | — | — | EP | claimed |