Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.88 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.88 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605020 | 0.93 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL30366103 | 0.93 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL30366182 | 0.87 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL28590230 | 0.87 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL28585805 | 0.84 | PIK3CD (0.78) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL28595358 | 0.83 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL2673524 | 0.82 | PIK3CD (0.73) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL190336 | 0.82 | PIK3CD (0.86) | PIK3CDPIK3CAPIK3CG | |
| SCHEMBL2675377 | 0.82 | PIK3CD (0.70) | PIK3CDPIK3CA | |
| SCHEMBL28591509 | 0.81 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920199-B | Piperazinone substituent or derivative thereof, preparation method and application thereof, and pharmaceutical composition | 四川大学 | 2023-02-03 | — | — | CN | disclosed |
| CN-112920199-A | Piperazinone substituent or derivative thereof, and preparation method, application and pharmaceutical composition thereof | 四川大学 | 2021-06-08 | — | — | CN | disclosed |