Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MIF | P14174 | 7/20 | 1.00 |
| ▸ | NPC1 | O15118 | 4/20 | 0.74 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.74 |
| ▸ | RAB9A | P51151 | 2/20 | 0.74 |
| ▸ | MEN1 | O00255 | 1/20 | 0.74 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.74 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.74 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.74 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.67 |
| ▸ | ATM | Q13315 | 1/20 | 0.67 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.67 |
| ▸ | MAOB | P27338 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.62 |
| ▸ | PKM | P14618 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.61 |
| ▸ | GAPDH | P04406 | 1/20 | 0.61 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30108442 | 1.00 | MIF (1.00) | MIFNPC1ERAP1RAB9AMEN1 | |
| SCHEMBL28843685 | 0.88 | MIF (0.80) | MIFNPC1ERAP1RAB9AMEN1 | |
| SCHEMBL949458 | 0.85 | MIF (1.00) | MIFNPC1ERAP1RAB9AMEN1 | |
| SCHEMBL29402681 | 0.85 | MIF (1.00) | MIFNPC1ERAP1RAB9AMEN1 | |
| SCHEMBL980362 | 0.85 | MIF (0.80) | MIFNPC1ERAP1RAB9AMEN1 | |
| SCHEMBL29427499 | 0.85 | MIF (0.72) | MIFNPC1ERAP1RAB9AMEN1 | |
| SCHEMBL5940809 | 0.85 | MIF (0.72) | MIFNPC1ERAP1RAB9AMEN1 | |
| SCHEMBL22132859 | 0.84 | MAOB (0.74) | MIFNPC1RAB9AMAOBGPR35 | |
| SCHEMBL22132870 | 0.81 | MAOB (0.82) | MIFNPC1RAB9AMAOBGAPDH | |
| SCHEMBL591688 | 0.81 | MIF (1.00) | MIFNPC1ERAP1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121485-B | 3-aryl coumarin derivative and preparation method and application thereof | 中山大学 | 2023-01-03 | — | — | CN | disclosed |
| CN-113121485-A | 3-aryl coumarin derivative and preparation method and application thereof | 中山大学 | 2021-07-16 | — | — | CN | disclosed |