Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STING1 | Q86WV6 | 18/20 | 0.81 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.80 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19451477 | 1.00 | STING1 (0.81) | STING1TBK1ENPP1 | |
| SCHEMBL29702099 | 1.00 | STING1 (0.81) | STING1TBK1ENPP1 | |
| SCHEMBL19451797 | 0.92 | STING1 (0.78) | STING1TBK1ENPP1 | |
| SCHEMBL19437661 | 0.91 | STING1 (0.87) | STING1TBK1ENPP1 | |
| SCHEMBL24467542 | 0.91 | STING1 (0.69) | STING1TBK1ENPP1 | |
| SCHEMBL19451482 | 0.91 | STING1 (0.80) | STING1TBK1 | |
| SCHEMBL24467533 | 0.91 | STING1 (0.80) | STING1TBK1 | |
| SCHEMBL29702073 | 0.91 | STING1 (0.93) | STING1TBK1ENPP1 | |
| SCHEMBL19451762 | 0.91 | STING1 (0.93) | STING1TBK1ENPP1 | |
| SCHEMBL19451865 | 0.90 | STING1 (0.76) | STING1TBK1ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113549110-A | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-10-26 | — | — | CN | disclosed |
| CN-109608443-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-09-07 | — | — | CN | disclosed |
| CN-109071514-B | Heterocyclic amides as protein modulators | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-06 | — | — | CN | disclosed |