Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 10/20 | 0.44 |
| ▸ | MME | P08473 | 9/20 | 0.44 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | CTSL | P07711 | 1/20 | 0.43 |
| ▸ | CTSS | P25774 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28607514 | 0.90 | ACE2 (0.46) | ACE2ECE1MME | |
| SCHEMBL28607881 | 0.89 | NPC1 (0.45) | ACE2ECE1MME | |
| SCHEMBL23881820 | 0.87 | MEN1 (0.47) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL28596357 | 0.86 | MME (0.41) | ACE2ECE1MMECTSKCTSL | |
| SCHEMBL28598146 | 0.85 | ACE2 (0.46) | ACE2ECE1MME | |
| SCHEMBL28597382 | 0.84 | ATM (0.51) | ACE2ECE1MMECTSKCTSL | |
| SCHEMBL28601704 | 0.84 | PLAU (0.43) | ACE2ECE1MME | |
| SCHEMBL28610449 | 0.83 | F2 (0.47) | ACE2ECE1MME | |
| SCHEMBL28607517 | 0.83 | ACE2 (0.43) | MAPTSMN1; SMN2ACE2ECE1MME | |
| SCHEMBL28607515 | 0.82 | ACE2 (0.45) | LMNAMAPTACE2ECE1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166182-A | Aminopeptidase A inhibitor and pharmaceutical composition comprising the same | 量子基因公司 | 2021-07-23 | — | — | CN | disclosed |