SCHEMBL2859856

SCHEMBL2859856

CC/C(C(=O)O)=C(/O)C(=O)O

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FFAR3 O14843 2/20 0.44
GRIK1 P39086 2/20 0.38
GRIA4 P48058 1/20 0.38
GRIK3 Q13003 1/20 0.38
GRIK5 Q16478 1/20 0.38
TDP1 Q9NUW8 2/20 0.37
ALDH1A1 P00352 1/20 0.37
THRB P10828 1/20 0.34
FNTA P49354 1/20 0.34
FNTB P49356 1/20 0.34
PGGT1B P53609 1/20 0.34
HDAC3 O15379 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC2 Q92769 1/20 0.32
HDAC8 Q9BY41 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2852463 1.00 FFAR3 (0.44) FFAR3GRIK1GRIA4GRIK3GRIK5
SCHEMBL42603 0.83 FFAR3 (0.53) FFAR3GRIK1GRIA4GRIK3GRIK5
SCHEMBL42601 0.83 FFAR3 (0.53) FFAR3GRIK1GRIA4GRIK3GRIK5
SCHEMBL101165 0.83 FFAR3 (0.53) FFAR3GRIK1GRIA4GRIK3GRIK5
Hydrochloric Acid SCHEMBL9622192 0.80 FFAR3 (0.50) FFAR3GRIK1GRIA4GRIK3GRIK5
SCHEMBL304061 0.80 FFAR3 (0.50) FFAR3GRIK1GRIA4GRIK3GRIK5
Potassium SCHEMBL305430 0.80 FFAR3 (0.50) FFAR3GRIK1GRIA4GRIK3GRIK5
SCHEMBL304063 0.80 FFAR3 (0.50) FFAR3GRIK1GRIA4GRIK3GRIK5
SCHEMBL305428 0.80 FFAR3 (0.50) FFAR3GRIK1GRIA4GRIK3GRIK5
SCHEMBL27684567 0.80 FFAR3 (0.50) FFAR3GRIK1GRIA4GRIK3GRIK5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2199333-B1 Binder-strengthened textile sheet, method for its production and application JOHNS MANVILLE EUROPE GMBH (DE) 2012-10-24 EP disclosed
EP-2199333-A1 Binder-strengthened textile sheet, method for its production and application Johns Manville Europe GmbH (DE) 2010-06-23 EP disclosed
EP-1622963-A2 RADIATION CURABLE THIOL-ENE COMPOSITION DSM IP Assets B.V. (NL) 2006-02-08 EP disclosed
WO-2004101649-A2 RADIATION CURABLE THIOL-ENE COMPOSITION DSM IP ASSETS B.V. (NL) 2004-11-25 WO disclosed