Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 10/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.66 |
| ▸ | HPGD | P15428 | 8/20 | 0.66 |
| ▸ | NPC1 | O15118 | 6/20 | 0.66 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 3/20 | 0.66 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.66 |
| ▸ | TSHR | P16473 | 1/20 | 0.66 |
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | GAA | P10253 | 4/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.63 |
| ▸ | KIT | P10721 | 2/20 | 0.59 |
| ▸ | FLT3 | P36888 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 4/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL770038 | 0.92 | MAPT (0.72) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL770399 | 0.92 | MAPT (0.64) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL769828 | 0.88 | KDM4E (0.67) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL769865 | 0.88 | MAPT (0.69) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL769649 | 0.88 | KDM4E (0.67) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL769548 | 0.88 | MAPT (0.64) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL770393 | 0.87 | MAPT (0.66) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL769848 | 0.87 | MAPT (0.69) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL770591 | 0.87 | MAPT (0.66) | MAPTALDH1A1KDM4EHPGDNPC1 | |
| SCHEMBL769090 | 0.87 | KIT (0.77) | MAPTALDH1A1KDM4EHPGDNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113234022-A | Benzimidazole derivative and synthesis method and application thereof | 中国人民解放军军事科学院军事医学研究院军事认知与脑科学研究所 | 2021-08-10 | — | — | CN | claimed |
| CN-113234022-A | Benzimidazole derivative and synthesis method and application thereof | 中国人民解放军军事科学院军事医学研究院军事认知与脑科学研究所 | 2021-08-10 | — | — | CN | disclosed |
| CN-113234022-A | Benzimidazole derivative and synthesis method and application thereof | 中国人民解放军军事科学院军事医学研究院军事认知与脑科学研究所 | 2021-08-10 | — | — | CN | disclosed |