Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACKR3 | P25106 | 1/20 | 0.60 |
| ▸ | USP30 | Q70CQ3 | 10/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.49 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
| ▸ | HPGDS | O60760 | 1/20 | 0.46 |
| ▸ | UCHL1 | P09936 | 1/20 | 0.46 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.46 |
| ▸ | FEN1 | P39748 | 1/20 | 0.46 |
| ▸ | BCHE | P06276 | 1/20 | 0.44 |
| ▸ | HTR6 | P50406 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19017744 | 1.00 | ACKR3 (0.60) | ACKR3USP30KDM4EPKMMKNK1 | |
| SCHEMBL18987073 | 0.86 | USP30 (0.67) | USP30MKNK1UCHL1 | |
| SCHEMBL18987075 | 0.86 | USP30 (0.67) | USP30MKNK1UCHL1 | |
| SCHEMBL28497363 | 0.85 | MKNK1 (0.67) | ACKR3USP30MKNK1MMP1MMP13 | |
| SCHEMBL19296045 | 0.85 | MKNK1 (0.67) | ACKR3USP30MKNK1MMP1MMP13 | |
| SCHEMBL14408031 | 0.78 | CKS1B (0.56) | ACKR3USP30KDM4EPKMMKNK1 | |
| SCHEMBL4593791 | 0.77 | KDR (0.46) | ACKR3USP30KDM4EPKMMKNK1 | |
| SCHEMBL23545071 | 0.76 | USP30 (0.59) | ACKR3USP30MKNK1MMP1MMP13 | |
| SCHEMBL20936958 | 0.76 | USP30 (0.59) | ACKR3USP30MKNK1MMP1MMP13 | |
| SCHEMBL29501551 | 0.76 | USP30 (0.59) | ACKR3USP30MKNK1MMP1MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368089-B | Deubiquitinase inhibitor | 特殊治疗有限公司 | 2021-07-06 | — | — | CN | disclosed |