Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | POLA1 | P09884 | 1/20 | 0.61 |
| ▸ | PPARG | P37231 | 8/20 | 0.59 |
| ▸ | PPARA | Q07869 | 8/20 | 0.59 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.54 |
| ▸ | PPARD | Q03181 | 6/20 | 0.54 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.54 |
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | TLR2 | O60603 | 2/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | FABP4 | P15090 | 2/20 | 0.54 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.54 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.54 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | ESR1 | P03372 | 1/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1427171 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 | |
| SCHEMBL4451405 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 | |
| SCHEMBL2707172 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 | |
| SCHEMBL646383 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 | |
| SCHEMBL4451407 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 | |
| SCHEMBL15841982 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 | |
| SCHEMBL14622019 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 | |
| SCHEMBL8985149 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 | |
| SCHEMBL1427172 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 | |
| SCHEMBL13044267 | 1.00 | POLB (0.61) | POLBPOLA1PPARGPPARATRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107261148-B | Methylphenidate prodrugs, methods of making and using the same | 凯姆制药公司 | 2021-07-13 | — | — | CN | disclosed |