Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 2/20 | 0.64 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | TDO2 | P48775 | 1/20 | 0.49 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.47 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 1/20 | 0.43 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.42 |
| ▸ | ACACA | Q13085 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | JAK3 | P52333 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19017745 | 1.00 | USP30 (0.64) | USP30IDO1TDO2MAP4K1GPR119 | |
| SCHEMBL29908199 | 1.00 | USP30 (0.64) | USP30IDO1TDO2MAP4K1GPR119 | |
| SCHEMBL18987031 | 0.88 | USP30 (0.70) | USP30MAP4K1WNT1GSK3BDYRK1A | |
| SCHEMBL18987030 | 0.88 | USP30 (0.70) | USP30MAP4K1WNT1GSK3BDYRK1A | |
| SCHEMBL28592475 | 0.85 | IDO1 (0.55) | USP30IDO1TDO2GPR119IRAK1 | |
| SCHEMBL19017746 | 0.85 | IDO1 (0.55) | USP30IDO1TDO2GPR119IRAK1 | |
| SCHEMBL29908216 | 0.85 | IDO1 (0.55) | USP30IDO1TDO2GPR119IRAK1 | |
| SCHEMBL18987182 | 0.81 | USP30 (0.65) | USP30IDO1TDO2GPR119IRAK1 | |
| SCHEMBL18987177 | 0.78 | USP30 (1.00) | USP30MAP4K1 | |
| SCHEMBL24659688 | 0.72 | KDM1A (0.56) | IDO1TDO2GPR119IRAK1CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108368089-B | Deubiquitinase inhibitor | 特殊治疗有限公司 | 2021-07-06 | — | — | CN | disclosed |