SCHEMBL28600353

SCHEMBL28600353

CC(C)C[C@H](OC(N)=O)C(=O)NS(=O)(=O)c1cccc(-c2ccnc(O)n2)c1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
LARS1 Q9P2J5 10/20 0.65
TARS1 P26639 7/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28600354 1.00 LARS1 (0.65) LARS1TARS1
SCHEMBL19792916 0.86 LARS1 (0.85) LARS1TARS1
SCHEMBL28601928 0.83 LARS1 (0.76) LARS1TARS1
SCHEMBL28601926 0.83 LARS1 (0.76) LARS1TARS1
SCHEMBL17977203 0.83 LARS1 (0.64) LARS1TARS1
SCHEMBL31650931 0.80 LARS1 (0.58) LARS1TARS1
SCHEMBL19792920 0.80 LARS1 (0.58) LARS1TARS1
SCHEMBL28591683 0.79 LARS1 (0.51) LARS1
SCHEMBL28591685 0.79 LARS1 (0.51) LARS1
SCHEMBL19792911 0.79 LARS1 (1.00) LARS1TARS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107257789-B Novel N-acyl-arylsulfonamide derivatives as aminoacyl-TRNA synthetase inhibitors 牛津药物设计有限公司 2021-06-29 CN disclosed