Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.54 |
| ▸ | PTGDR2 | Q9Y5Y4 | 7/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.43 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.41 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28605203 | 0.91 | HDAC6 (0.53) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28618257 | 0.90 | HDAC6 (0.56) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28609703 | 0.89 | HDAC6 (0.58) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28617759 | 0.88 | HDAC6 (0.54) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28607613 | 0.85 | HDAC6 (0.54) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28619052 | 0.84 | HDAC6 (0.53) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28920569 | 0.84 | HDAC6 (0.60) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28609734 | 0.82 | HDAC6 (0.64) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28618140 | 0.81 | HDAC6 (0.61) | HDAC6PTGDR2HDAC1HDAC10HDAC8 | |
| SCHEMBL28609619 | 0.80 | PTGDR2 (0.48) | HDAC6PTGDR2HDAC1HDAC10HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113121527-A | Tricyclic compound and use thereof | 上海辉启生物医药科技有限公司 | 2021-07-16 | — | — | CN | disclosed |