Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IGF1R | P08069 | 8/20 | 0.41 |
| ▸ | JAK2 | O60674 | 5/20 | 0.41 |
| ▸ | JAK3 | P52333 | 5/20 | 0.41 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.41 |
| ▸ | JAK1 | P23458 | 2/20 | 0.40 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.40 |
| ▸ | FLT4 | P35916 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30956458 | 0.93 | DYRK2 (0.42) | IGF1RJAK2JAK3PTK2JAK1 | |
| SCHEMBL29249023 | 0.91 | FLT4 (0.42) | IGF1RJAK2JAK3PTK2FLT4 | |
| SCHEMBL30956628 | 0.90 | DYRK2 (0.40) | IGF1RJAK2JAK3PTK2JAK1 | |
| SCHEMBL24852446 | 0.89 | JAK3 (0.52) | IGF1RJAK2JAK3PTK2DYRK2 | |
| SCHEMBL26970754 | 0.86 | JAK2 (0.43) | IGF1RJAK2JAK3PTK2JAK1 | |
| SCHEMBL24852475 | 0.86 | JAK2 (0.43) | IGF1RJAK2JAK3PTK2JAK1 | |
| SCHEMBL30754120 | 0.86 | JAK2 (0.43) | IGF1RJAK2JAK3PTK2JAK1 | |
| SCHEMBL22098035 | 0.85 | DYRK2 (0.44) | IGF1RJAK2JAK3PTK2JAK1 | |
| SCHEMBL24853547 | 0.85 | JAK3 (0.44) | IGF1RJAK2JAK3PTK2JAK1 | |
| SCHEMBL24852530 | 0.83 | IGF1R (0.46) | IGF1RJAK2JAK3JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290403-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl and compositions and methods thereof | 凌科药业(杭州)有限公司 | 2024-07-05 | — | — | CN | disclosed |
| CN-113227074-A | Benzamide derivatives of pyrazolyl-amino-pyrimidinyl derivatives, compositions and methods | 凌科药业(杭州)有限公司 | 2021-08-06 | — | — | CN | disclosed |