Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.78 |
| ▸ | HTR2A | P28223 | 2/20 | 0.78 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.78 |
| ▸ | HRH2 | P25021 | 1/20 | 0.78 |
| ▸ | HTR2B | P41595 | 1/20 | 0.78 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.78 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601084 | 1.00 | SLC6A2 (0.78) | SLC6A2HTR2ASLC6A3HRH2HTR2B | |
| SCHEMBL28438949 | 0.88 | SLC6A2 (1.00) | SLC6A2HTR2ASLC6A3HRH2HTR2B | |
| SCHEMBL28438946 | 0.88 | SLC6A2 (1.00) | SLC6A2HTR2ASLC6A3HRH2HTR2B | |
| SCHEMBL28608576 | 0.85 | SLC6A2 (0.74) | SLC6A2HTR2ASLC6A3HRH2HTR2B | |
| SCHEMBL28608578 | 0.85 | SLC6A2 (0.74) | SLC6A2HTR2ASLC6A3HRH2HTR2B | |
| SCHEMBL28591137 | 0.84 | SLC6A2 (0.93) | SLC6A2HTR2ASLC6A3HRH2HTR2B | |
| SCHEMBL10326528 | 0.83 | CHRNB4 (0.70) | — | |
| SCHEMBL10326784 | 0.83 | CHRNB4 (0.70) | — | |
| SCHEMBL10326293 | 0.83 | CHRNB4 (0.70) | — | |
| SCHEMBL28603662 | 0.79 | SLC6A2 (0.74) | SLC6A2HTR2ASLC6A3HRH2HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107459510-B | Isoxazole compound and application thereof | 华东师范大学 | 2021-06-25 | — | — | CN | disclosed |