Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K1 | Q92918 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20516709 | 0.88 | MAP4K1 (0.61) | MAP4K1 | |
| SCHEMBL28602791 | 0.83 | MAP4K1 (0.69) | MAP4K1 | |
| SCHEMBL21827166 | 0.82 | MAP4K1 (0.70) | MAP4K1 | |
| SCHEMBL21872772 | 0.77 | MAP4K1 (0.71) | MAP4K1 | |
| SCHEMBL21874617 | 0.75 | MAP4K1 (0.81) | MAP4K1 | |
| SCHEMBL28609774 | 0.74 | MAP4K1 (0.60) | MAP4K1 | |
| SCHEMBL28609829 | 0.74 | MAP4K1 (0.60) | MAP4K1 | |
| SCHEMBL28609775 | 0.74 | MAP4K1 (0.60) | MAP4K1 | |
| SCHEMBL21860012 | 0.74 | MAP4K1 (1.00) | MAP4K1 | |
| SCHEMBL21860253 | 0.74 | MAP4K1 (1.00) | MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166062-A | 8-aminoisoquinoline compounds and uses thereof | 豪夫迈·罗氏有限公司 | 2021-07-23 | — | — | CN | disclosed |