Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL27907864 | 0.83 | TDP1 (0.56) | TDP1TSHRALDH1A1 | |
| Propylene Glycol SCHEMBL28109391 | 0.82 | — | — | |
| SCHEMBL7696717 | 0.82 | — | — | |
| SCHEMBL306604 | 0.82 | — | — | |
| SCHEMBL465102 | 0.82 | — | — | |
| Propylene Glycol SCHEMBL7065356 | 0.79 | TDP1 (0.50) | TDP1TSHR | |
| Propylene Glycol SCHEMBL2551258 | 0.79 | TDP1 (0.50) | TDP1TSHR | |
| Propylene Glycol SCHEMBL28346127 | 0.78 | — | — | |
| Propylene Glycol SCHEMBL28901001 | 0.77 | — | — | |
| Propylene Glycol SCHEMBL28133001 | 0.77 | TDP1 (0.62) | TDP1TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112844387-B | Difunctional ferronickel hydrotalcite catalyst and preparation method and application thereof | 山西大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-112844387-A | Difunctional ferronickel hydrotalcite catalyst and preparation method and application thereof | 山西大学 | 2021-05-28 | — | — | CN | disclosed |