Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.53 |
| ▸ | NR1H4 | Q96RI1 | 18/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2856977 | 0.92 | CNR2 (0.51) | CNR2NR1H4CNR1TDP1 | |
| SCHEMBL2860129 | 0.91 | CNR2 (0.50) | CNR2NR1H4CNR1TDP1 | |
| SCHEMBL2861508 | 0.86 | CNR2 (0.42) | CNR2NR1H4CNR1TDP1 | |
| SCHEMBL13513508 | 0.84 | CNR2 (0.41) | CNR2NR1H4CNR1TDP1 | |
| SCHEMBL13711653 | 0.81 | LTB4R2 (0.40) | CNR2NR1H4 | |
| SCHEMBL13711679 | 0.81 | NR1H4 (0.44) | CNR2NR1H4CNR1TDP1 | |
| SCHEMBL2857129 | 0.79 | CNR2 (0.36) | CNR2NR1H4 | |
| SCHEMBL2852877 | 0.79 | CNR2 (0.42) | CNR2NR1H4CNR1TDP1 | |
| SCHEMBL13711787 | 0.79 | CNR2 (0.53) | CNR2NR1H4CNR1TDP1 | |
| SCHEMBL13711781 | 0.78 | LTB4R2 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1654247-B1 | ALKYNYL ARYL CARBOXAMIDES | MERCK SERONO SA (CH) | 2010-01-20 | — | — | EP | disclosed |