Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Pyrrole. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pyrrole SCHEMBL27743676 | 1.00 | — | — | |
| Pyrrole SCHEMBL173774 | 1.00 | — | — | |
| Pyrrole SCHEMBL27647186 | 0.95 | — | — | |
| Pyrrole SCHEMBL27934381 | 0.95 | — | — | |
| Pyrrole SCHEMBL28049758 | 0.95 | — | — | |
| Pyrrole SCHEMBL841068 | 0.94 | — | — | |
| Pyrrole SCHEMBL2885785 | 0.94 | — | — | |
| Pyrrole SCHEMBL292 | 0.94 | — | — | |
| Pyrrole SCHEMBL15757584 | 0.94 | — | — | |
| Pyrrole SCHEMBL27535135 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164571-A | Inhibition of ubiquitin-specific peptidase 9X | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |