Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22595136 | 0.95 | EGFR (0.72) | EGFR | |
| Trifluoroacetic Acid SCHEMBL22587624 | 0.94 | EGFR (0.72) | EGFR | |
| Trifluoroacetic Acid SCHEMBL22587810 | 0.92 | EGFR (0.72) | EGFR | |
| Trifluoroacetic Acid SCHEMBL22588447 | 0.90 | EGFR (0.65) | EGFR | |
| Trifluoroacetic Acid SCHEMBL22587631 | 0.90 | EGFR (0.67) | EGFR | |
| SCHEMBL22595217 | 0.89 | EGFR (0.70) | EGFR | |
| Trifluoroacetic Acid SCHEMBL28596174 | 0.88 | EGFR (0.64) | EGFR | |
| SCHEMBL22595222 | 0.88 | EGFR (0.70) | EGFR | |
| SCHEMBL22596185 | 0.88 | EGFR (0.80) | EGFR | |
| SCHEMBL22595213 | 0.88 | EGFR (0.77) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166103-B | EGFR inhibitor and application thereof | 江苏先声药业有限公司 | 2022-12-16 | — | — | CN | disclosed |
| CN-113166103-A | EGFR inhibitor and application thereof | 江苏先声药业有限公司 | 2021-07-23 | — | — | CN | disclosed |