Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ABL1 | P00519 | 1/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.36 |
| ▸ | RET | P07949 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.36 |
| ▸ | FLT3 | P36888 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.36 |
| ▸ | MAP4K2 | Q12851 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | NTRK2 | Q16620 | 1/20 | 0.36 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1119491 | 0.77 | TDP1 (0.41) | CHEK1DAPK3JAK2ABL1NTRK1 | |
| Hydrochloric Acid SCHEMBL27791573 | 0.75 | TDP1 (0.43) | CHEK1DAPK3JAK2ABL1NTRK1 | |
| Hydrochloric Acid SCHEMBL10604762 | 0.75 | TDP1 (0.43) | CHEK1DAPK3JAK2ABL1NTRK1 | |
| SCHEMBL7682594 | 0.72 | CHEK1 (0.38) | CHEK1DAPK3JAK2ABL1NTRK1 | |
| SCHEMBL7679797 | 0.72 | TDP1 (0.37) | TDP1ALDH1A1CYP3A4KDM4EHSD17B10 | |
| SCHEMBL31607640 | 0.70 | CHEK1 (0.49) | CHEK1DAPK3JAK2ABL1NTRK1 | |
| Tannin Pyrogallol SCHEMBL7671493 | 0.70 | HSD17B10 (0.50) | CHEK1TUBB4ATUBBTUBA3CTUBA1B | |
| SCHEMBL3788849 | 0.70 | CHEK1 (0.36) | CHEK1DAPK3JAK2ABL1NTRK1 | |
| SCHEMBL1484216 | 0.69 | CHEK1 (0.39) | CHEK1DAPK3JAK2ABL1NTRK1 | |
| SCHEMBL3786304 | 0.68 | FYN (0.42) | FLT3TUBB4ATUBBTUBA3CTUBA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112961170-B | Sponge source actinomycetes and preparation method and application of sulfur-containing alkaloid produced by sponge source actinomycetes | 中国科学院南海海洋研究所 | 2022-03-11 | — | — | CN | disclosed |
| CN-112961170-A | Sponge source actinomycetes and preparation method and application of novel sulfur-containing alkaloid produced by sponge source actinomycetes | 中国科学院南海海洋研究所 | 2021-06-15 | — | — | CN | disclosed |