Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 16/20 | 0.71 |
| ▸ | CRBN | Q96SW2 | 16/20 | 0.71 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.60 |
| ▸ | TNF | P01375 | 1/20 | 0.60 |
| ▸ | IL1B | P01584 | 1/20 | 0.60 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.60 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.54 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | STAT3 | P40763 | 1/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.51 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26318031 | 0.95 | DDB1 (0.78) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL26318034 | 0.95 | DDB1 (0.78) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL26321362 | 0.95 | DDB1 (0.78) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL2382531 | 0.95 | DDB1 (0.78) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL29794467 | 0.95 | DDB1 (0.78) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL31292080 | 0.88 | DDB1 (0.66) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL26317715 | 0.86 | CRBN (0.66) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL23751736 | 0.85 | DDB1 (0.76) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL16569284 | 0.84 | DDB1 (0.82) | DDB1CRBNIKZF3TNFIL1B | |
| SCHEMBL18546682 | 0.84 | DDB1 (0.82) | DDB1CRBNIKZF3TNFIL1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112512589-A | Dimeric immunomodulatory compounds against CEREBLON-based mechanisms | H·李·莫菲特癌症中心研究有限公司 | 2021-03-16 | — | — | CN | disclosed |