Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | JAK3 | P52333 | 18/20 | 0.55 |
| ▸ | JAK1 | P23458 | 2/20 | 0.55 |
| ▸ | BTK | Q06187 | 10/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28601837 | 1.00 | JAK3 (0.55) | JAK3JAK1BTK | |
| SCHEMBL22497063 | 0.89 | JAK3 (0.71) | JAK3JAK1BTK | |
| SCHEMBL22497066 | 0.89 | JAK3 (0.71) | JAK3JAK1BTK | |
| SCHEMBL22497084 | 0.86 | JAK3 (0.62) | JAK3JAK1BTK | |
| SCHEMBL22497082 | 0.86 | JAK3 (0.62) | JAK3JAK1BTK | |
| SCHEMBL22496767 | 0.85 | JAK1 (0.53) | JAK3JAK1BTK | |
| SCHEMBL29448466 | 0.85 | JAK1 (0.53) | JAK3JAK1BTK | |
| SCHEMBL28596543 | 0.85 | JAK1 (0.53) | JAK3JAK1BTK | |
| SCHEMBL28610634 | 0.83 | BTK (0.53) | JAK3BTK | |
| SCHEMBL28610635 | 0.83 | BTK (0.53) | JAK3BTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311896-B | Pyrazolopyrimidine derivatives as kinase inhibitors | 株式会社大熊制药 | 2021-08-24 | — | — | CN | disclosed |
| CN-113135920-A | Pyrazolopyrimidine derivatives as kinase inhibitors | 株式会社大熊制药 | 2021-07-20 | — | — | CN | disclosed |