Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 3/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.59 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.57 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.45 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.45 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.44 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.44 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.44 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.44 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28596582 | 0.81 | HIF1A (0.62) | HDAC1HDAC6HDAC8HIF1ASMN1; SMN2 | |
| SCHEMBL892664 | 0.79 | SNCA (0.59) | — | |
| SCHEMBL28606422 | 0.78 | HIF1A (0.61) | HIF1ARIPK1TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL28608110 | 0.78 | HIF1A (0.61) | HDAC1HDAC6HDAC8HIF1ARIPK1 | |
| SCHEMBL1114337 | 0.78 | KMT2A (0.49) | HDAC1HDAC6HDAC8SMN1; SMN2ALDH1A1 | |
| SCHEMBL28597825 | 0.77 | HIF1A (0.67) | HIF1ARIPK1SMN1; SMN2P2RX7ALDH1A1 | |
| SCHEMBL2559848 | 0.76 | HDAC6 (0.77) | HDAC1HDAC6HDAC8TSHRALDH1A1 | |
| SCHEMBL5598218 | 0.74 | HIF1A (0.85) | HIF1ARIPK1SMN1; SMN2P2RX7LMNA | |
| SCHEMBL8160653 | 0.73 | HIF1A (1.00) | HIF1ASMN1; SMN2P2RX7LMNATRPV1 | |
| SCHEMBL2104880 | 0.73 | HDAC6 (0.77) | HDAC1HDAC6HDAC8TSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |