Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 11/20 | 0.72 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | KLF5 | Q13887 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28344737 | 0.84 | HIF1A (1.00) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL28598211 | 0.84 | HIF1A (1.00) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL28345384 | 0.82 | HIF1A (0.88) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL28348077 | 0.81 | HIF1A (0.86) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL28347976 | 0.81 | HIF1A (0.84) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL28594259 | 0.81 | HIF1A (0.84) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL28347862 | 0.80 | HIF1A (0.83) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL28603560 | 0.79 | HIF1A (1.00) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL28348304 | 0.79 | HIF1A (0.81) | HIF1ARAB9ANPC1MEN1KMT2A | |
| SCHEMBL937246 | 0.78 | HIF1A (0.62) | HIF1ARAB9ANPC1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110407824-B | Aryl formamide compound and preparation method, pharmaceutical composition and application thereof | 安徽医科大学 | 2021-07-02 | — | — | CN | disclosed |