Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 20/20 | 0.88 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.69 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.69 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28587358 | 0.94 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL28604999 | 0.85 | PIK3CD (0.87) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL28595358 | 0.85 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL28590230 | 0.85 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL30366182 | 0.85 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL28585805 | 0.85 | PIK3CD (0.78) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL30366628 | 0.84 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL28591522 | 0.84 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL28609220 | 0.82 | PIK3CD (0.88) | PIK3CDPIK3CAPIK3CGPIK3CB | |
| SCHEMBL28917741 | 0.82 | PIK3CD (1.00) | PIK3CDPIK3CAPIK3CGPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112920199-A | Piperazinone substituent or derivative thereof, and preparation method, application and pharmaceutical composition thereof | 四川大学 | 2021-06-08 | — | — | CN | disclosed |