Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR1 | Q92633 | 14/20 | 0.84 |
| ▸ | LPAR3 | Q9UBY5 | 7/20 | 0.77 |
| ▸ | LPAR2 | Q9HBW0 | 2/20 | 0.66 |
| ▸ | ABCC3 | O15438 | 1/20 | 0.65 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.65 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.65 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | ABCB4 | P21439 | 1/20 | 0.65 |
| ▸ | ABCC2 | Q92887 | 1/20 | 0.65 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.65 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.65 |
| ▸ | KLK7 | P49862 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12070816 | 0.92 | LPAR1 (0.84) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2293657 | 0.92 | LPAR1 (0.82) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2292240 | 0.92 | LPAR1 (0.82) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2292246 | 0.92 | LPAR1 (0.82) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL15280711 | 0.91 | LPAR1 (0.85) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2288084 | 0.91 | LPAR1 (1.00) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2288090 | 0.91 | LPAR1 (1.00) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL2296696 | 0.91 | LPAR1 (1.00) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL12070818 | 0.90 | LPAR1 (0.80) | LPAR1LPAR3LPAR2ABCC3ABCC4 | |
| SCHEMBL29354386 | 0.89 | LPAR1 (0.85) | LPAR1LPAR3LPAR2ABCC3ABCC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105142635-B | Heterocyclic compounds useful for the treatment of diseases | 艾匹根生物技术有限公司 | 2021-07-27 | — | — | CN | disclosed |