⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702036 | 0.74 | — | — | |
| SCHEMBL5702035 | 0.74 | — | — | |
| SCHEMBL251766 | 0.72 | — | — | |
| SCHEMBL901205 | 0.72 | — | — | |
| SCHEMBL7559471 | 0.72 | — | — | |
| SCHEMBL10425115 | 0.70 | — | — | |
| SCHEMBL1846490 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL1846488 | 0.70 | TSHR (0.33) | — | |
| SCHEMBL9060309 | 0.69 | — | — | |
| SCHEMBL9060304 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 902 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118267479-A | Combination therapy using chemokine receptor 2 (CCR 2) antagonists and PD-1/PD-L1 inhibitors | 凯莫森特里克斯股份有限公司 | 2024-07-02 | — | — | CN | claimed |
| CN-118139621-A | Method for amplifying erythroid precursor cells or erythroblasts and application thereof | 北京大学 | 2024-06-04 | — | — | CN | claimed |
| EP-3474845-B1 | IMMUNOMODULATOR COMPOUNDS | CHEMOCENTRYX INC (US) | 2024-03-20 | — | — | EP | claimed |
| WO-2024026273-A1 | THERAPY FOR REDUCED OTOTOXICITY FROM CHEMOTHERAPEUTIC AGENT WITH PENTAAZA MACROCYCLIC RING COMPLEX | GALERA LABS, LLC (US) | 2024-02-01 | — | — | WO | claimed |
| CN-114524934-B | Application of polypeptide polymer or polypeptide mimic in bone repair | 华东理工大学 | 2024-01-30 | — | — | CN | claimed |
| US-20230420260-A1 | POLISHING LIQUID COMPOSITION FOR SILICON OXIDE FILM | KAO CORPORATION (JP) | 2023-12-28 | — | — | US | claimed |
| CN-117285707-A | Preparation method and application of beta-polypeptide polymer with low toxicity and high antibacterial activity | 华东理工大学 | 2023-12-26 | — | — | CN | claimed |
| US-11793771-B2 | Immunomodulator compounds | CHEMOCENTRYX, INC. (US) | 2023-10-24 | — | — | US | claimed |
| US-11759458-B2 | Indane-amines as PD-L1 antagonists | CHEMOCENTRYX, INC. (US) | 2023-09-19 | — | — | US | claimed |
| US-20230279266-A1 | POLISHING LIQUID COMPOSITION FOR SILICON OXIDE FILMS | KAO CORPORATION (JP) | 2023-09-07 | — | — | US | claimed |
| EP-0228192-A2 | Renin-inhibitory oligopeptides, their preparation and use | SANKYO COMPANY LIMITED (JP) | 1987-07-08 | — | — | EP | claimed |
| CN-86101850-A | N, the manufacture method and the purposes of N '-dialkyl group guanidine radicals dipeptides | — | 1987-02-04 | — | — | CN | claimed |
| US-4544557-A | ANTIBIOTICS | MERCK & CO., INC. (US) | 1985-10-01 | — | — | US | claimed |
| US-4450170-A | A P-AMINO CLONIDINE ALONG WITH AN ORAL HYDRATION AGENT; ANTISECRETORY AGENTS | BEECHAM GROUP LIMITED (GB) | 1984-05-22 | — | — | US | claimed |
| US-4366309-A | MACROLACTONES | SCHERING CORPORATION (US) | 1982-12-28 | — | — | US | claimed |
| US-4237217-A | IN WHICH COUPLING POSITION IS SUBSTITUTED WITH A SULFONAMIDO GROUP | FUJI PHOTO FILM CO., LTD. (JP) | 1980-12-02 | — | — | US | claimed |
| EP-0012401-A1 | Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them | MERCK & CO. INC. (US) | 1980-06-25 | — | — | EP | claimed |
| US-4191574-A | AZO-METHINE DYES | KONISHIROKU PHOTO INDUSTRY CO., LTD. (JP) | 1980-03-04 | — | — | US | claimed |
| US-4113637-A | DISPERSANTS, DETERGENTS | INSTITUT FRANCAIS DU PETROLE (FR) | 1978-09-12 | — | — | US | claimed |
| US-4071459-A | Alkyl-guanidino-heterocyclic compounds, their manufacture and use as additives for fuels and lubricants | INSTITUT FRANCAIS DU PETROLE (FR) | 1978-01-31 | — | — | US | claimed |