Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.42 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.41 |
| ▸ | CTSG | P08311 | 4/20 | 0.41 |
| ▸ | CTRB1 | P17538 | 4/20 | 0.41 |
| ▸ | CMA1 | P23946 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 4/20 | 0.38 |
| ▸ | CES1 | P23141 | 4/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL4577876 | 0.89 | TSHR (0.44) | TSHRDAONAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1784532 | 0.86 | TSHR (0.47) | TSHRDAONAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1784685 | 0.84 | TSHR (0.45) | TSHRDAONAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1784796 | 0.84 | DAO (0.45) | TSHRDAONAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1786954 | 0.84 | DAO (0.48) | TSHRDAONAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL27642058 | 0.83 | TSHR (0.44) | TSHRDAONAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL4577351 | 0.81 | RARB (0.42) | TSHRDAONAPRTCES2CES1 | |
| Benzoic Acid SCHEMBL27523532 | 0.81 | DAO (0.41) | TSHRDAONAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1785721 | 0.81 | TSHR (0.41) | TSHRDAONAPRTPRSS1CTSG | |
| Benzoic Acid SCHEMBL1784704 | 0.80 | TSHR (0.44) | TSHRDAONAPRTPRSS1CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478846-A | Carrier of catalyst with function of catalyzing olefin polymerization, preparation method and application of carrier, olefin polymerization catalyst and application of olefin polymerization catalyst | 中国石油化工股份有限公司 | 2022-05-13 | — | — | CN | disclosed |
| CN-109678996-B | Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-109678998-B | Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2021-11-19 | — | — | CN | disclosed |
| CN-109679006-B | Catalyst component and catalyst system for olefin polymerization, prepolymerized catalyst system and olefin polymerization method | 中国石油化工股份有限公司 | 2021-08-03 | — | — | CN | disclosed |