Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 20/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2860520 | 1.00 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL13604426 | 0.90 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL4505936 | 0.90 | FFAR1 (0.38) | FFAR1 | |
| SCHEMBL13604425 | 0.88 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL2854632 | 0.88 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL2854630 | 0.88 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL13604427 | 0.80 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL4517856 | 0.80 | FFAR1 (0.40) | FFAR1 | |
| SCHEMBL2856341 | 0.79 | NOTUM (0.43) | FFAR1 | |
| SCHEMBL2856340 | 0.79 | NOTUM (0.43) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1805141-B1 | PIPERIDINES AND RELATED COMPOUNDS FOR TREATMENT OF ALZHEIMER'S DISEASE | MERCK SHARP & DOHME (GB) | 2010-01-20 | — | — | EP | disclosed |