Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IAPP | P10997 | 4/20 | 0.61 |
| ▸ | TYR | P14679 | 1/20 | 0.54 |
| ▸ | PRKCI | P41743 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SHBG | P04278 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25307580 | 0.87 | IAPP (0.53) | IAPPTYRPRKCIALDH1A1MEN1 | |
| SCHEMBL5201499 | 0.81 | TYR (0.49) | IAPPTYRPRKCIALDH1A1MEN1 | |
| SCHEMBL15354662 | 0.81 | TYR (0.50) | IAPPTYRPRKCIALDH1A1MEN1 | |
| SCHEMBL28919441 | 0.80 | IAPP (0.50) | IAPPALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL21224062 | 0.76 | TYR (0.72) | IAPPTYRPRKCIMEN1KMT2A | |
| SCHEMBL8402774 | 0.76 | TYR (0.85) | TYRPRKCIMEN1KMT2AMAPT | |
| SCHEMBL70108 | 0.76 | TYR (0.60) | TYRPRKCIMEN1KMT2AMAPT | |
| SCHEMBL29131809 | 0.76 | IAPP (0.58) | IAPPTYRPRKCI | |
| SCHEMBL3652663 | 0.75 | TYR (0.51) | IAPPTYRPRKCIALDH1A1MEN1 | |
| SCHEMBL1405042 | 0.74 | IAPP (0.51) | IAPPPRKCIALDH1A1LMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109293493-B | Novel benzhydryl compounds with mycobacterium tuberculosis inhibiting activity | 清华大学 | 2021-08-03 | — | — | CN | disclosed |