Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 20/20 | 1.00 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.81 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.81 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.81 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30011234 | 0.90 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL28611076 | 0.85 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29970516 | 0.84 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL28611073 | 0.84 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL28608594 | 0.84 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| Hydrochloric Acid SCHEMBL28601913 | 0.83 | PIK3CA (1.00) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29970518 | 0.82 | PIK3CA (0.83) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL28599149 | 0.81 | PIK3CA (0.81) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL29970025 | 0.81 | PIK3CA (0.81) | PIK3CAPIK3CDPIK3CBPIK3CG | |
| SCHEMBL28617236 | 0.80 | PIK3CA (0.78) | PIK3CAPIK3CDPIK3CBPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200969-B | PI3K alpha selective inhibitor and preparation method and application thereof | 中国药科大学 | 2022-11-25 | — | — | CN | disclosed |
| WO-2022242321-A1 | PI3Kα SELECTIVE INHIBITOR, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | 中国药科大学 | 2022-11-24 | — | — | WO | disclosed |
| CN-113200969-A | PI3K alpha selective inhibitor and preparation method and application thereof | 中国药科大学 | 2021-08-03 | — | — | CN | disclosed |