Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 6/20 | 0.56 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.56 |
| ▸ | HDAC2 | Q92769 | 6/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 5/20 | 0.56 |
| ▸ | HDAC7 | Q8WUI4 | 5/20 | 0.56 |
| ▸ | HDAC10 | Q969S8 | 5/20 | 0.56 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.56 |
| ▸ | HDAC9 | Q9UKV0 | 5/20 | 0.56 |
| ▸ | HDAC5 | Q9UQL6 | 5/20 | 0.56 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | CA7 | P43166 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.45 |
| ▸ | TTR | P02766 | 1/20 | 0.42 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16382705 | 1.00 | HDAC3 (0.56) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL10412422 | 0.86 | HDAC1 (0.47) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL9331716 | 0.86 | HDAC1 (0.47) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL26246354 | 0.84 | MAPT (0.52) | HDAC1HDAC2CA12CA1CA2 | |
| SCHEMBL2577796 | 0.83 | HDAC1 (0.66) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL2577800 | 0.83 | HDAC1 (0.66) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8852985 | 0.81 | TTR (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL8852995 | 0.81 | TTR (0.43) | HDAC3HDAC1HDAC2HDAC8HDAC6 | |
| SCHEMBL29860671 | 0.78 | CA12 (0.44) | CA12CA1CA2CA7CA9 | |
| SCHEMBL28656322 | 0.77 | CA12 (0.39) | HDAC3HDAC1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113164571-A | Inhibition of ubiquitin-specific peptidase 9X | 福马治疗股份有限公司 | 2021-07-23 | — | — | CN | disclosed |