Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 18/20 | 0.70 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.70 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.70 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.70 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.70 |
| ▸ | EGFR | P00533 | 1/20 | 0.70 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.70 |
| ▸ | BRD4 | O60885 | 2/20 | 0.58 |
| ▸ | BRDT | Q58F21 | 2/20 | 0.58 |
| ▸ | BRD2 | P25440 | 1/20 | 0.58 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.58 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.57 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.57 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.57 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.57 |
| ▸ | PRKCG | P05129 | 1/20 | 0.57 |
| ▸ | LCK | P06239 | 1/20 | 0.57 |
| ▸ | LYN | P07948 | 1/20 | 0.57 |
| ▸ | RET | P07949 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29842187 | 1.00 | MAPK14 (0.70) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL29841951 | 1.00 | MAPK14 (0.70) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL28615850 | 1.00 | MAPK14 (0.70) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL20550491 | 0.99 | MAPK14 (0.69) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL29841960 | 0.98 | MAPK14 (0.70) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL28607656 | 0.98 | MAPK14 (0.70) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL29841930 | 0.95 | MAPK14 (0.67) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL28601290 | 0.95 | MAPK14 (0.67) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL29842097 | 0.93 | MAPK14 (0.65) | MAPK14MAPK13CSNK1DMAPK12MAPK11 | |
| SCHEMBL28610718 | 0.93 | MAPK14 (0.65) | MAPK14MAPK13CSNK1DMAPK12MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113272298-A | Compounds and compositions for the treatment of respiratory diseases | 墨尔本大学 | 2021-08-17 | — | — | CN | disclosed |