Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.41 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.40 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 8/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | ADH1C | P00326 | 1/20 | 0.39 |
| ▸ | ADH1A | P07327 | 1/20 | 0.39 |
| ▸ | ADH4 | P08319 | 1/20 | 0.39 |
| ▸ | ADH7 | P40394 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL7610276 | 1.00 | TSHR (0.41) | TSHRZDHHC20ZDHHC2EPHX1ADH1B | |
| Bromide SCHEMBL28902968 | 1.00 | TSHR (0.41) | TSHRZDHHC20ZDHHC2EPHX1ADH1B | |
| Bromide SCHEMBL28619519 | 1.00 | TSHR (0.41) | TSHRZDHHC20ZDHHC2EPHX1ADH1B | |
| Bromide SCHEMBL5550545 | 1.00 | TSHR (0.41) | TSHRZDHHC20ZDHHC2EPHX1ADH1B | |
| Bromide SCHEMBL4580370 | 1.00 | TSHR (0.41) | TSHRZDHHC20ZDHHC2EPHX1ADH1B | |
| Bromide SCHEMBL7610283 | 1.00 | TSHR (0.41) | TSHRZDHHC20ZDHHC2EPHX1ADH1B | |
| SCHEMBL1137491 | 0.98 | TSHR (0.43) | TSHRZDHHC20ZDHHC2EPHX1ADH1B | |
| SCHEMBL11897227 | 0.98 | TSHR (0.43) | TSHRZDHHC20ZDHHC2EPHX1ADH1B | |
| SCHEMBL1137388 | 0.98 | TSHR (0.43) | TSHRZDHHC20ZDHHC2EPHX1ADH1B | |
| Hydrochloric Acid SCHEMBL9123249 | 0.96 | TSHR (0.41) | TSHRZDHHC20ZDHHC2EPHX1ADH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135744-B | Attapulgite/mica/carbon composite material and preparation method thereof | 浙江凯色丽科技发展有限公司 | 2022-04-01 | — | — | CN | disclosed |
| CN-113135744-A | Attapulgite/mica/carbon composite material and preparation method thereof | 浙江凯色丽科技发展有限公司 | 2021-07-20 | — | — | CN | disclosed |