Acetone

Acetone

SCHEMBL28609082

CC(C)=O.CC(C)=O.c1cc(-c2ccncc2)ccn1

nearest known ligand 0.65

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.65
LMNA P02545 1/20 0.65
NOTUM Q6P988 1/20 0.52
HDAC1 Q13547 1/20 0.52
HDAC6 Q9UBN7 1/20 0.52
CSNK1A1 P48729 1/20 0.50
CSNK1D P48730 1/20 0.50
CLK2 P49760 1/20 0.50
CSNK1G1 Q9HCP0 1/20 0.50
KIF11 P52732 2/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PABPC1 P11940 1/20 0.48
APOBEC3A P31941 1/20 0.48
EIF4H Q15056 1/20 0.48
APOBEC3G Q9HC16 1/20 0.48
NAPRT Q6XQN6 1/20 0.48
CCNC P24863 3/20 0.47
CDK8 P49336 3/20 0.47
TP53 P04637 1/20 0.46
QDPR P09417 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetone SCHEMBL27959679 1.00 MAPT (0.65) MAPTLMNANOTUMHDAC1HDAC6
Acetic Acid SCHEMBL28340433 0.85 NOTUM (0.71) MAPTLMNANOTUMHDAC1HDAC6
Methyl Alcohol SCHEMBL28030205 0.84 MAPT (0.79) MAPTLMNANOTUMHDAC1HDAC6
SCHEMBL1138817 0.83 MAPT (0.61) MAPTLMNAHDAC1HDAC6CSNK1A1
Ethane SCHEMBL27940957 0.81 MAPT (0.85) MAPTLMNANOTUMHDAC1HDAC6
SCHEMBL9728 0.80 MAPT (1.00) MAPTLMNANOTUMHDAC1HDAC6
SCHEMBL3728246 0.78 SMN1; SMN2 (0.76) MAPTHDAC1SMN1; SMN2NAPRTALDH1A1
Hydrochloric Acid SCHEMBL3930145 0.77 MAPT (0.92) MAPTLMNANOTUMHDAC1HDAC6
Water SCHEMBL1648462 0.77 MAPT (0.92) MAPTLMNANOTUMHDAC1HDAC6
Hydrogen Sulfide SCHEMBL3929756 0.77 MAPT (0.92) MAPTLMNANOTUMHDAC1HDAC6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113171798-A Heterogeneous iron catalyst, preparation method thereof and process for preparing 2-methyl-1, 4-naphthoquinone through catalysis 南京工业大学 2021-07-27 CN disclosed