Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.42 |
| ▸ | CYP17A1 | P05093 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29816471 | 1.00 | KDM4E (0.46) | KDM4EMAPTCA12CA1CA9 | |
| SCHEMBL16412251 | 0.86 | KDM4E (0.49) | KDM4EMAPTCA12CA1CA9 | |
| SCHEMBL596681 | 0.84 | KDM4E (0.64) | KDM4EMAPTCA12CA1CA9 | |
| SCHEMBL4969811 | 0.84 | CA12 (0.53) | KDM4EMAPTCA12CA1CA9 | |
| SCHEMBL30339301 | 0.84 | KDM4E (0.64) | KDM4EMAPTCA12CA1CA9 | |
| SCHEMBL30258184 | 0.84 | CA12 (0.53) | KDM4EMAPTCA12CA1CA9 | |
| SCHEMBL1854623 | 0.82 | MAPT (0.54) | KDM4EMAPTCA12CA1CA9 | |
| SCHEMBL15388323 | 0.82 | PPARG (0.49) | KDM4EMAPTCA12CA1CA9 | |
| SCHEMBL19233276 | 0.82 | KDM4E (0.46) | KDM4EMAPTCA12CA1CA9 | |
| SCHEMBL30640612 | 0.82 | MAPT (0.54) | KDM4EMAPTCA12CA1CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113200908-B | Tertiary amine-containing anthranilamide compound and preparation and application thereof | 南华大学 | 2022-07-19 | — | — | CN | disclosed |
| CN-113200908-A | Tertiary amine-containing anthranilamide compound and preparation and application thereof | 南华大学 | 2021-08-03 | — | — | CN | disclosed |