Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPM1B | O75688 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9083292 | 0.83 | PPM1B (0.43) | PPM1BPTPN1PPP1CCALDH1A1LMNA | |
| SCHEMBL9083280 | 0.83 | PPM1B (0.43) | PPM1BPTPN1PPP1CCALDH1A1LMNA | |
| SCHEMBL14400889 | 0.83 | PPM1B (0.43) | PPM1BPTPN1PPP1CCALDH1A1LMNA | |
| SCHEMBL4415431 | 0.83 | PPM1B (0.43) | PPM1BPTPN1PPP1CCALDH1A1LMNA | |
| SCHEMBL14393314 | 0.83 | PPM1B (0.43) | PPM1BPTPN1PPP1CCALDH1A1LMNA | |
| SCHEMBL4521342 | 0.83 | PPM1B (0.43) | PPM1BPTPN1PPP1CCALDH1A1LMNA | |
| SCHEMBL25885236 | 0.82 | PPM1B (0.45) | PPM1BPTPN1PPP1CCHCAR2ALDH1A1 | |
| SCHEMBL836017 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL4415434 | 0.81 | PPM1B (0.42) | PPM1BPTPN1PPP1CCTSHRALDH1A1 | |
| Hydrochloric Acid SCHEMBL4415429 | 0.81 | PPM1B (0.42) | PPM1BPTPN1PPP1CCTSHRALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108299270-B | Preparation method of disubstituted pyrrole compound | 中国科学院宁波材料技术与工程研究所 | 2021-08-17 | — | — | CN | disclosed |