⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003526 | 0.79 | — | — | |
| SCHEMBL17591495 | 0.76 | — | — | |
| SCHEMBL28028477 | 0.75 | HDAC8 (0.41) | — | |
| Hydrochloric Acid SCHEMBL27986785 | 0.74 | — | — | |
| SCHEMBL28656121 | 0.72 | — | — | |
| SCHEMBL14824324 | 0.72 | — | — | |
| SCHEMBL9804376 | 0.72 | — | — | |
| SCHEMBL28265860 | 0.72 | — | — | |
| SCHEMBL28934730 | 0.72 | — | — | |
| SCHEMBL28301409 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113135937-B | Fused tetracyclic compound and application thereof in medicines | 广东东阳光药业股份有限公司 | 2024-11-08 | — | — | CN | disclosed |
| CN-117384204-B | Enol silicon ether compound, preparation method and application thereof | 康龙化成手性医药技术(宁波)有限公司 | 2024-08-23 | — | — | CN | disclosed |
| CN-117384204-A | Enol silicon ether compound, preparation method and application thereof | 康龙化成手性医药技术(宁波)有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117362316-A | Synthesis method of tetrahydropyrrolothiazole compound | 康龙化成手性医药技术(宁波)有限公司 | 2024-01-09 | — | — | CN | disclosed |
| CN-113135937-A | Fused tetracyclic compounds and application thereof in medicines | 广东东阳光药业有限公司 | 2021-07-20 | — | — | CN | disclosed |