Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 19/20 | 0.58 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.41 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21796758 | 0.86 | LRRK2 (0.51) | LRRK2MAP4K1 | |
| SCHEMBL28619667 | 0.84 | LRRK2 (0.46) | LRRK2KMO | |
| SCHEMBL17573299 | 0.75 | LRRK2 (0.70) | LRRK2 | |
| SCHEMBL17573300 | 0.74 | LRRK2 (1.00) | LRRK2 | |
| SCHEMBL21796777 | 0.73 | LRRK2 (0.41) | LRRK2 | |
| SCHEMBL17573378 | 0.73 | LRRK2 (1.00) | LRRK2MAP4K1 | |
| SCHEMBL17573292 | 0.73 | LRRK2 (1.00) | LRRK2MAP4K1 | |
| SCHEMBL17573293 | 0.72 | LRRK2 (1.00) | LRRK2MAP4K1 | |
| SCHEMBL22324916 | 0.72 | HPGD (0.45) | KMO | |
| SCHEMBL21796915 | 0.72 | LRRK2 (0.55) | LRRK2KMO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108137510-B | Compound (I) | 葛兰素史密斯克莱知识产权发展有限公司 | 2021-07-20 | — | — | CN | disclosed |